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神经影像学的临床实践要点Essentials of Neuroimaging for Clinical Practice.pdf Essentials of Neuroimaging for Clinical Practice This page intentionally left blank Washington, DC London, England Essentials of Neuroimaging for Clinical Practice Edited by Darin D. Dougherty, M.D., M.Sc. Scott L. Rauch, M.D. Jerrold F. Rosenbaum, M.D. Note: The authors have worked to ensure that all information in this book is accurate at the time of publication and consistent with general psychiatric and medical standards, and that information concerning drug dosages, schedules, and routes of administration is accurate at the time of publication and consistent with standards set by the U.S. Food and Drug Administration and the general medical community. As medical research and practice continue to advance, however, therapeutic standards may change. Moreover, specific situations may require a spe- cific therapeutic response not included in this book. For these reasons and because human and mechanical errors sometimes occur, we recommend that readers follow the advice of physicians directly involved in their care or the care of a member of their family. Books published by American Psychiatric Publishing, Inc., represent the views and opinions of the individual au- thors and do not necessarily represent the policies and opinions of APPI or the American Psychiatric Association. Copyright © 2004 American Psychiatric Publishing, Inc. ALL RIGHTS RESERVED Manufactured in the United States of America on acid-free paper 08 07 06 05 04 5 4 3 2 1 First Edition Typeset in Adobe’s Palatino and Futura Book American Psychiatric Publishing, Inc. 1000 Wilson Boulevard Arlington, VA 22209–3901 www.appi.org Library of Congress Cataloging-in-Publication Data Essentials of neuroimaging for clinical practice / edited by Darin D. Dougherty, Scott L. Rauch, Jerrold F. Rosenbaum p. ; cm. Includes bibliographical references and index. ISBN 1-58562-079-3 (alk. paper) 1. Brain—Imaging. I. Dougherty, Darin D. II. Rauch, Scott L. III. Rosenbaum, J. F. (Jerrold F.) [DNLM: 1. Diagnostic Imaging. 2. Mental Disorders—diagnosis. WM 141 E78 2003] RC386.6.D52E84 2003 616.8’04754—dc21 2003052221 British Library Cataloguing in Publication Data A CIP record is available from the British Library. About the cover: Top (left and right): Effect of image acquisition parameters on functional magnetic resonance imaging (fMRI) signal. Middle: Color-coded diffusion tensor imaging (DTI): Anisotropy (left) and color-coded DTI (right) of a healthy con- trol subject. Source. Reprinted from Taber KH, Pierpaoli C, Rose SE, et al.: “The Future for Diffusion Tensor Imag- ing in Neuropsychiatry.” Journal of Neuropsychiatry and Clinical Neurosciences 14:1–5, 2002. Copyright 2002. Used with permission. Bottom left: Acute embolic stroke on computed tomography (CT) (hypodense lesion indicated by arrow). Bottom right: 15-Oxygen positron emission tomography (15O PET) data acquired from a patient during an acute ischemic event. ...